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Papers of the Week

Papers: 6 Jun 2020 - 12 Jun 2020

Human Studies

2020 Jun 05

Eur J Pain

Within- and between-session reliability of secondary hyperalgesia induced by electrical high-frequency stimulation.


Cayrol T, Lebleu J, Mouraux A, Roussel N, Pitance L, Van Den Broeke EN
Eur J Pain. 2020 Jun 05.
PMID: 32501583.


An increasing number of studies are focusing on secondary hyperalgesia to better understand central sensitization, as this phenomenon may play an important role in persistent pain. Recent studies have shown that, compared to the classical high frequency stimulation protocol (HFS) at 100 Hz, a protocol using 42 Hz stimulation induces a more intense and a larger area of secondary hyperalgesia (SH).