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Papers of the Week

Papers: 9 May 2020 - 15 May 2020

Animal Studies

2020 Jun




Local Sympathectomy Promotes Anti-inflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice.


Tonello R, Xie W, Lee S, Wang M, Liu X, Strong JA, Zhang J-M, Berta T
Anesthesiology. 2020 Jun; 132(6):1540-1553.
PMID: 32404819.


Patients undergoing cancer treatment often experience chemotherapy-induced neuropathic pain at their extremities, for which there is no U.S. Food and Drug Administration-approved drug. The authors hypothesized that local sympathetic blockade, which is used in the clinic to treat various pain conditions, can also be effective to treat chemotherapy-induced neuropathic pain.