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Papers of the Week

Papers: 18 Apr 2020 - 24 Apr 2020

Human Studies

2020 Apr 21

Arthritis Res Ther



Predictors of the use of analgesic drugs 1 year after joint replacement: a single-center analysis of 13,000 hip and knee replacements.


Rajamäki T J, Puolakka PA, Hietaharju A, Moilanen T, Jämsen E
Arthritis Res Ther. 2020 Apr 21; 22(1):89.
PMID: 32317021.


Pain persists in a moderate number of patients following hip or knee replacement surgery. Persistent pain may subsequently lead to the prolonged consumption of analgesics after surgery and expose patients to the adverse drug events of opioids and NSAIDs, especially in older patients and patients with comorbidities. This study aimed to identify risk factors for the increased use of opioids and other analgesics 1 year after surgery and focused on comorbidities and surgery-related factors.