I am a
Home I AM A Search Login

Papers of the Week

2020 Mar 24

J Clin Med



Aryl Hydrocarbon Receptor Activation Downregulates IL-33 Expression in Keratinocytes via Ovo-Like 1.


Tsuji G, Hashimoto-Hachiya A, Yen V H, Miake S, Takemura M, Mitamura Y, Ito T, Murata M, Furue M, Nakahara T
J Clin Med. 2020 Mar 24; 9(3).
PMID: 32214018.


IL-33, one of the IL-1 superfamily cytokines, has been shown to be associated with pruritus and inflammation in atopic dermatitis (AD). Furthermore, IL-33 production derived from keratinocytes reportedly has a crucial role in the development of AD; however, the mechanism of IL-33 expression has not been fully understood.