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Papers of the Week

Papers: 25 Jan 2020 - 31 Jan 2020


Human Studies

2020 04

Reg Anesth Pain Med



Centralized pain and pain catastrophizing mediate the association between lifetime abuse history and self-reported pain medication side effects.


Pierce J, Hassett AL, Schneiderhan JR, Divers J, Brummett CM, Goesling J
Reg Anesth Pain Med. 2020 04; 45(4):293-300.
PMID: 31988267.


Self-reported side effects of pain medication are important determinants of treatment course that can affect patient adherence, medication discontinuation and physician decisions. Yet, few studies have investigated patient-level predictors of self-reported pain medication side effects. The present study sought to fill this gap by exploring the impact of physical or sexual abuse history on self-reported pain medication side effects and considered a mediation model in which those effects are transmitted through a centralized pain phenotype and pain catastrophizing.