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Papers of the Week


Papers: 18 Jan 2020 - 24 Jan 2020


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2020 Jan 17


BMC Neurol


20


1

Safety and tolerability of monthly galcanezumab injections in patients with migraine: integrated results from migraine clinical studies.

Authors

Bangs ME, Kudrow D, Wang S, Oakes TM, Terwindt GM, Magis D, Yunes-Medina L, Stauffer VL
BMC Neurol. 2020 Jan 17; 20(1):25.
PMID: 31952501.

Abstract

Galcanezumab, a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days in phase 2 and 3 trials. In these analyses, we aimed to evaluate the safety and tolerability of galcanezumab compared with placebo for prevention of episodic or chronic migraine.