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Papers of the Week

2020 Mar

Clin Drug Investig



Comparison of the Efficacy and Safety of Pregabalin and Duloxetine in Taxane-Induced Sensory Neuropathy: A Randomized Controlled Trial.


Salehifar E, Janbabaei G, Hendouei N, Alipour A, Tabrizi N, Avan R
Clin Drug Investig. 2020 Mar; 40(3):249-257.
PMID: 31925721.


Taxane-induced peripheral neuropathy (TIPN) is a main toxicity of taxanes with no effective treatment. This study aimed to compare the efficacy and safety of pregabalin (150 mg daily) and duloxetine (60 mg daily) for managing TIPN in breast cancer patients.