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Papers of the Week


2020 Mar


Clin Drug Investig


40


3

Comparison of the Efficacy and Safety of Pregabalin and Duloxetine in Taxane-Induced Sensory Neuropathy: A Randomized Controlled Trial.

Authors

Salehifar E, Janbabaei G, Hendouei N, Alipour A, Tabrizi N, Avan R
Clin Drug Investig. 2020 Mar; 40(3):249-257.
PMID: 31925721.

Abstract

Taxane-induced peripheral neuropathy (TIPN) is a main toxicity of taxanes with no effective treatment. This study aimed to compare the efficacy and safety of pregabalin (150 mg daily) and duloxetine (60 mg daily) for managing TIPN in breast cancer patients.