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Papers of the Week
Malabaricone C attenuates NSAID-induced gastric ulceration by reducing oxidative/nitrative stress and inflammation and promoting angiogenic auto-healing.
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs), amongst the most commonly used drugs worldwide, are associated with gastrointestinal complications that severely limit the clinical utility of this essential class of pain medications. Here, we mechanistically dissect the protective impact of a natural product, malabaricone C, on NSAID-induced gastropathy.