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Papers of the Week
The effects of long-term opioid treatment on the immune system in chronic non-cancer pain patients: A systematic review.
Abstract
Opioids have been increasingly prescribed for chronic non-cancer pain (CNCP). An association between long-term opioid treatment (L-TOT) of CNCP patients and suppression of both the innate and the adaptive immune system has been proposed. This systematic review aims at investigating the effects of L-TOT on the immune system in CNCP patients.