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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial.

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Papers: 28 Sep 2019 - 4 Oct 2019


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Itch


2019 Dec 01


JAMA Dermatol


http://www.ncbi.nlm.nih.gov/pubmed/31577341?dopt=Abstract


155


12

Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial.

Authors

Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial.
Gooderham MJ, Forman SB, Bissonnette R, Beebe JS, Zhang W, Banfield C, Zhu L, Papacharalambous J, Vincent MS, Peeva E
JAMA Dermatol. 2019 Dec 01; 155(12):1371-1379.
PMID: 31577341.

Abstract

Atopic dermatitis is associated with substantial patient and caregiver burden. Currently available treatments for atopic dermatitis are inadequate or contraindicated for some patients. Abrocitinib (PF-04965842) is an oral Janus kinase 1 selective inhibitor under investigation for the treatment of atopic dermatitis.
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