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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Intrathecally injected tramadol reduces articular incapacitation and edema in a rat model of lipopolysaccharide (LPS)-induced reactive arthritis.

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2019 Nov 01


Life Sci


http://www.ncbi.nlm.nih.gov/pubmed/31518605?dopt=Abstract


236

Intrathecally injected tramadol reduces articular incapacitation and edema in a rat model of lipopolysaccharide (LPS)-induced reactive arthritis.

Authors

Intrathecally injected tramadol reduces articular incapacitation and edema in a rat model of lipopolysaccharide (LPS)-induced reactive arthritis.
Lucena F, Callado de Oliveira DMM, Norões MM, Mujica EMM, Melleu FF, de Benedet PO, Stein T, Ribeiro LFC, Tonussi CR
Life Sci. 2019 Nov 01; 236:116860.
PMID: 31518605.

Abstract

Intrathecal injection of morphine presents analgesic and antiedematogenic effects in rats. However, it is unknown whether tramadol, which possess a mixed mechanism of action, can also produce analgesic and antiedematogenic effects similarly.
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