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Papers of the Week

Papers: 18 May 2019 - 24 May 2019

Human Studies

2020 Jun 01

Pain Med



Expression of Cutaneous Beta-2 Adrenoceptors Is Similar in Patients with Complex Regional Pain Syndrome and Pain-Free Controls.


Drummond PD, Morellini N, Visser E, Finch PM
Pain Med. 2020 Jun 01; 21(6):1199-1207.
PMID: 31120123.


Studies in rodents suggest that cutaneous beta-2 adrenoceptors (β2-ARs) mediate inflammation and pain after tissue injury and that inflammation and peripheral nerve injury trigger increases in neuronal β2-AR expression. Hence, the aim of this study was to investigate the expression of β2-ARs on keratinocytes and dermal nerves in patients with complex regional pain syndrome (CRPS).