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Papers of the Week
Mast Cells Get on Your Nerves in Itch.
Authors
PMID: 31117004.
Abstract
Mast-cell-nerve interactions play an integral role in itch and inflammation. Meixiong et al. (2019) show that the receptors MRGPRB2 and FcεRI mediate distinct types of mast cell activation and nerve interactions and that mast cell activation through MRGPRB2 drives itch in allergic contact dermatitis.