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Papers of the Week

Papers: 23 Feb 2019 - 1 Mar 2019

2020 Feb 01




Deep Brain Stimulation for Pain in the Modern Era: A Systematic Review.


Frizon LA, Yamamoto EA, Nagel SJ, Simonson MT, Hogue O, Machado AG
Neurosurgery. 2020 Feb 01; 86(2):191-202.
PMID: 30799493.


Deep brain stimulation (DBS) has been considered for patients with intractable pain syndromes since the 1950s. Although there is substantial experience reported in the literature, the indications are contested, especially in the United States where it remains off-label. Historically, the sensory-discriminative pain pathways were targeted. More recently, modulation of the affective sphere of pain has emerged as a plausible alternative.