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Papers of the Week

Papers: 16 Feb 2019 - 22 Feb 2019

Animal Studies

2019 Feb 19

BMC Genomics



Sex differences in gene regulation in the dorsal root ganglion after nerve injury.


Stephens KE, Zhou W, Ji Z, Chen Z, He S, Ji H, Guan Y, Taverna SD
BMC Genomics. 2019 Feb 19; 20(1):147.
PMID: 30782122.


Pain is a subjective experience derived from complex interactions among biological, environmental, and psychosocial pathways. Sex differences in pain sensitivity and chronic pain prevalence are well established. However, the molecular basis underlying these sex dimorphisms are poorly understood particularly with regard to the role of the peripheral nervous system. Here we sought to identify shared and distinct gene networks functioning in the peripheral nervous systems that may contribute to sex differences of pain in rats after nerve injury.