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Papers of the Week

Papers: 2 Feb 2019 - 8 Feb 2019

Human Studies, Pharmacology/Drug Development

2020 Jan

J Palliat Care



A Pilot Randomized Sham-Controlled Trial of MC5-A Scrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy (CIPN).


Smith TJ, Razzak RA, Blackford AL, Ensminger J, Saiki C, Longo-Schoberlein D, Loprinzi CL
J Palliat Care. 2020 Jan; 35(1):53-58.
PMID: 30714486.


Chemotherapy-induced peripheral neuropathy (CIPN) affects 30% to 40% of patients with cancer with long-lasting disability. Scrambler therapy (ST) appeared to benefit patients in uncontrolled trials, so we performed a randomized sham-controlled Phase II trial of ST.