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Accuracy of retrospective pain measurement in patients with chronic pain.

The use of pain scales that refer to a past time period is thereby based on the assumption that patients accurately remember their ‘average’, ‘greatest’ and ‘least’ pain. The present […]

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Referred pain: characteristics, possible mechanisms, and clinical management.

Referred pain is a common but less understood symptom that originates from somatic tissues. A comprehensive recognition of referred pain is important for clinicians when dealing with it. The purpose […]

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First study to assess the reliability of commonly used pain scales in children with disorders of gut-brain interaction.

There are no validated measures to assess chronic abdominal pain (AP) in clinical trials of children with disorders of gut-brain interaction (DGBIs). Currently used AP measures are extrapolated from studies […]

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Assessing the Feasibility of a Multimodal Approach to Pain Evaluation in Early Stages after Spinal Cord Injury.

This research evaluates the feasibility of a multimodal pain assessment protocol during rehabilitation following spinal cord injury (SCI). The protocol amalgamates clinical workup (CW), quantitative sensory testing (QST), and psychosocial […]

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Pharmacogenetic Guided Opioid Therapy Improves Chronic Pain Outcomes and Comorbid Mental Health: A Randomized, Double-Blind, Controlled Study.

Interindividual variability in analgesic response is at least partly due to well-characterized polymorphisms that are associated with opioid dosing and adverse outcomes. The Clinical Pharmacogenetics Implementation Consortium (CPIC) has put […]

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Analysis of Japanese nationwide health datasets: association between lifestyle habits and prevalence of neuropathic pain and fibromyalgia with reference to dementia-related diseases and Parkinson’s disease.

Chronic pain is defined as pain that persists or recurs for more than 3 months. This study focuses on neuropathic pain (NP) and fibromyalgia (FM) which are chronic pain states, and […]

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The human NTG model of migraine in drug discovery and development.

Various triggers can originate a migraine attack. In healthy volunteers and patients with migraine, the nitroglycerin (NTG) provocation model induces a headache that resembles migraine in pain characteristics and vascular […]

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Editorial: Updating amyloid neuropathy knowledge: from diagnosis to treatment.

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Migraine with aura detection and subtype classification using machine learning algorithms and morphometric magnetic resonance imaging data.

Migraine with aura (MwA) is a neurological condition manifested in moderate to severe headaches associated with transient visual and somatosensory symptoms, as well as higher cortical dysfunctions. Considering that about […]

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The Relationship Between Chronic Pain and Cognitive Impairment in the Elderly: A Review of Current Evidence.

Chronic pain and cognitive impairment are prevalent geriatric syndromes in the population of older adults, and they are the main cause of disability in people over sixty-five years of age. […]

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