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Human Studies

Home / Publications / Pain Research Forum / Papers of the Week / Human Studies
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Spinal Nerve Root Stimulation for Chronic Pain: A Systematic Review.

Spinal cord stimulation (SCS) has been used as a minimally invasive and effective treatment modality for various chronic pain disorders, with the main target being stimulation of the dorsal columns; […]

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Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations.

Endometriosis is a common estrogen-dependent disorder wherein uterine lining tissue (endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic pain, pain with intercourse and menses, and […]

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Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.

To systematically assess credibility and certainty of associations between cannabis, cannabinoids, and cannabis based medicines and human health, from observational studies and randomised controlled trials (RCTs).

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Interhemispheric inhibition between primary motor cortices is not altered in individuals with chronic lateral epicondylalgia.

Lateral epicondylalgia, commonly referred to as tennis elbow, is a musculoskeletal condition characterised by pain and sensorimotor dysfunction. In some individuals with chronic unilateral LE, sensorimotor symptoms develop on the […]

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Understanding chronic pain in the ubiquitous community: the role of open data.

The combined use of social media, open data, and Artificial Intelligence has the potential to support practitioners and empower patients/citizens living with persistent pain, both as local and online communities. […]

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Inflammation-related proteins as biomarkers of treatment-related behavioral symptoms: A longitudinal study of breast cancer patients and age-matched controls.

Behavioral symptoms in breast cancer (BC) survivors have been attributed to cancer treatment and resulting inflammation. However, studies linking behavioral symptoms to BC treatment have observed patients only after some […]

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Measures of sleep are not routinely captured in trials assessing treatment outcomes in knee osteoarthritis – A scoping systematic review and call to action.

To identify and map the extent to which trials for pain interventions in individuals with knee osteoarthritis (OA) track measures of sleep, characterize the type of sleep measure assessed, and […]

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Abnormal thalamo-cortical interactions in overlapping communities of migraine: an edge functional connectivity study.

Migraine has been demonstrated to exhibit abnormal functional connectivity of large-scale brain networks, which is closely associated with its pathophysiology and hasn’t yet been explored by edge functional connectivity. We […]

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A meta-analytic review of acceptance-based interventions for migraine.

To determine the efficacy of acceptance and mindfulness-based interventions on migraine disability, medication use, and attack frequency.

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Trigeminal Neuralgia as A Primary Demyelinating Disease: Potential Multimodal Evidence and Remaining Controversies.

Trigeminal neuralgia is a heterogeneous disorder with likely multifactorial and complex etiology; however, trigeminal nerve demyelination and injury is observed in almost all patients with trigeminal neuralgia. The current management […]

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