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Does active inference provide a comprehensive theory of placebo analgesia?

Placebo interventions generate mismatches between expected pain and sensory signals from which pain states are inferred. Since we lack direct access to bodily states, we can only infer whether nociceptive […]

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Systemic treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials.

Atopic dermatitis (AD) is an inflammatory skin condition with multiple systemic treatments and uncertainty regarding their comparative impact on AD outcomes.

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Topical treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials.

Atopic dermatitis (AD) is a common skin condition with multiple topical treatment options, but uncertain comparative effects.

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Randomized, double-blind, controlled trial of a combination of alpha-lipoic acid and pregabalin for neuropathic pain: the PAIN-CARE trial.

We compared a combination of the nonsedating antioxidant, alpha-lipoic acid (ALA), with the sedating anticonvulsant, pregabalin, vs each monotherapy to treat neuropathic pain due to peripheral neuropathies. In this randomized, […]

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Clinical and cognitive effects of external trigeminal nerve stimulation (eTNS) in neurological and psychiatric disorders: a systematic review and meta-analysis.

This pre-registered (CRD42022322038) systematic review and meta-analysis investigated clinical and cognitive outcomes of external trigeminal nerve stimulation (eTNS) in neurological and psychiatric disorders. PubMed, OVID, Web of Science, Chinese National […]

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Needling Point Location Used in Sham Acupuncture for Chronic Nonspecific Low Back Pain: A Systematic Review and Network Meta-Analysis.

When sham acupuncture is set as a control in evaluating acupuncture, the sham needling technique is usually different from acupuncture. However, the sham procedure is conducted either at the same […]

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Gabapentin Use Among Individuals Initiating Buprenorphine Treatment for Opioid Use Disorder.

Gabapentin prescriptions have drastically increased in the US due to off-label prescribing in settings such as opioid use disorder (OUD) treatment to manage a range of comorbid conditions and withdrawal […]

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Opioid-Free Discharge After Pancreatic Resection Through a Learning Health System Paradigm.

Postoperative opioid overprescribing leads to persistent opioid use and excess pills at risk for misuse and diversion. A learning health system paradigm using risk-stratified pancreatectomy clinical pathways (RSPCPs) may lead […]

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Atopic Dermatitis and risk for headache disorders and migraines: a population-based cohort study in children and adults from the United Kingdom.

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“Growing pains” in children and adolescents as an early symptom of migraine: A prospective study.

Children and adolescents may experience pain in the lower limbs, predominantly at the end of the day or during the night, without any relation to organic disease. These pains are […]

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