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Anti-calcitonin gene-related peptide monoclonal antibodies for the treatment of vestibular migraine: A prospective observational cohort study.

Vestibular migraine is considered the most common cause of recurrent vertigo for which specific treatments are missing. Monoclonal antibodies against calcitonin gene-related peptide are effective in preventing migraine. Since CGRP […]

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Both perimenstrual and non-perimenstrual migraine days respond to anti-calcitonin gene-related peptide (receptor) antibodies.

Anti-CGRP (receptor) antibodies effectively reduce overall migraine attack frequency, but whether there are differences in effect between perimenstrual and non-perimenstrual migraine days has not been investigated.

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Medication adherence in patients with cluster headache and migraine: an online survey.

To examine factors for adherent and non-adherent behavior in patients with cluster headache and migraine. Adults with cluster headache or migraine were included in this anonymous online survey using a […]

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Construct validity of Movement-Evoked pain operational definitions in older adults with chronic low back pain.

Movement-evoked pain (MeP) may predispose the geriatric chronic low back pain (LBP) population to health decline. Since there are differing operational definitions for MeP, the question remains as to whether […]

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Pain and insomnia as risk factors for first lifetime onsets of anxiety, depression, and suicidality in adolescence.

Chronic pain and mental health problems have both been identified as public health emergencies and co-occur at high rates. This prospective, longitudinal investigation examined whether chronic pain status, pain-related symptoms […]

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Rare variant analyses in large-scale cohorts identified SLC13A1 associated with chronic pain.

Chronic pain is a prevalent disease with increasing clinical challenges. Genome-wide association studies in chronic pain patients have identified hundreds of common pathogenic variants, yet they only explained a portion […]

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Conflicts hurt: social stress predicts elevated pain and sadness after mild inflammatory increases.

Individuals respond differently to inflammation. Pain, sadness, and fatigue are common correlates of inflammation among breast cancer survivors. Stress may predict response intensity. This study tested whether breast cancer survivors […]

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Effect modifiers of virtual reality in pain management: a systematic review and meta-regression analysis.

There is a rapidly growing body of evidence for the application of virtual reality (VR) in pain management, however, with varying effectiveness. Little is known about patient-related and VR-related factors […]

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Neural processing of pain-related distress to neck-specific movements in people with chronic whiplash-associated disorders.

Pain-related distress contributes to long-term disability in chronic whiplash-associated disorders. Recently, neuroimaging studies have revealed altered neural responses to viewing pictures of movements associated with back pain in key regions […]

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Abnormally Increased Effective Connectivity of the Periaqueductal Gray in Migraine Without Aura Patients.

The periaqueductal gray (PAG) is a key region in the descending pain modulatory system. We applied a Granger causality analysis-based approach to examine resting-state effective connectivity of the bilateral PAG […]

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