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Suffering out of sight but not out of mind – interpreting experiences of sick leave due to chronic pain in a community setting: a qualitative study.

Chronic pain is a complex health problem affecting about one-fifth of the European population. It is a leading cause of years lived with disability worldwide, with serious personal, relational and […]

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New botulinum neurotoxin constructs for treatment of chronic pain.

Chronic pain affects one in five people across human societies, with few therapeutic options available. Botulinum neurotoxin (BoNT) can provide long-lasting pain relief by inhibiting local release of neuropeptides and […]

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Prevalence and risk factors of depressive symptoms in children and adolescents with juvenile idiopathic arthritis.

Depression is a serious disorder disproportionately affecting people with chronic diseases, yet, to date is rarely recognized comorbidity in pediatric rheumatology clinical routine care. The aim of this study was […]

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Trends in Pain Medication Use in Patients With Type 2 Diabetes: NHANES 2005-2018.

The aim of this research was to compare pain medication use trends among adults with and without type 2 diabetes in the US. This cross-sectional study used data of adults […]

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Neurosurgical interventions for cancer pain.

Half of all cancer patients will develop cancer-related pain, and a fifth of these patients will continue to experience pain refractory to maximal pharmacological therapy. This, together with the opioid […]

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Prevalence and management of chronic nonmalignant pain in palliative care populations: A systematic review.

To investigate the prevalence and current approaches to clinical management of chronic nonmalignant pain in patients referred to palliative care services.

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IL-17 inhibitor-associated inflammatory bowel disease: A study based on literature and database analysis.

Few real-world studies have shown clear association between interleukin (IL)-17 inhibitors and inflammatory bowel disease (IBD) onset. This study investigated the reporting prevalence and evaluated the clinical features and management […]

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Telemedicine efficacy and satisfaction of patients and headache specialists in migraine management.

Migraine follow-up is difficult for outpatients, especially after the COVID-19 pandemic, we tried to identify the most appropriate telemedicine methods for migraine in terms of efficacy, safety, patient compliance, and […]

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Integrated analysis of genome-wide gene expression and DNA methylation profiles reveals candidate genes in ovary endometriosis.

The incidence of endometriosis (EMs), a common disease in gynecology, has increased over the years. Women suffer from the symptoms caused by EMs, such as chronic pelvic pain, dysmenorrhea, and […]

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Association of periodontal disease with migraine: A large-scale community-based cross-sectional study.

Periodontal disease may drive a systemic inflammatory response that triggers migraine; however, the association between periodontal disease and migraine has rarely been investigated in a community-based setting.

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