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The association between age and acute pain sensitivity in patients with Herpes Zoster.

Herpes zoster has a well-established increased incidence in older adults, but the relationship between age and acute pain severity remains less clear. This retrospective study aimed to explore the association […]

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Pharmacological Treatment of Chemotherapy-Induced Neuropathy: A Systematic Review of Randomized Clinical Trials.

Chemotherapy-induced peripheral neuropathy (CIPN) affects up to 80% of patients undergoing cytotoxic chemotherapy. This painful condition significantly impairs quality of life and often necessitates dose reduction or discontinuation of chemotherapy, […]

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Current and Evolving Concepts in the Management of Complex Regional Pain Syndrome: A Narrative Review.

: Complex regional pain syndrome (CRPS) is characterized by severe pain and reduced functionality, which can significantly affect an individual’s quality of life. The current treatment of CRPS is challenging. […]

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Comments on alleged editor misconduct from editors-in-chief of anaesthesia journals.

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Polymerized Type I Collagen Downregulates STAT-1 Phosphorylation Through Engagement with LAIR-1 in Circulating Monocytes, Avoiding Long COVID.

The intramuscular administration of polymerized type I collagen (PTIC) for adult symptomatic COVID-19 outpatients downregulated hyperinflammation and improved symptoms. We inferred that LAIR1 is a potential receptor for PTIC. Thus, […]

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Multi- and polypharmacology of carbonic anhydrase inhibitors.

Eight genetically distinct families of the enzyme carbonic anhydrase (CA, EC 4.2.1.1) have been described in organisms overall in the phylogenetic tree. They catalyze the hydration of CO to bicarbonate […]

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[The headache questionnaire of the German Migraine and Headache Society (DMKG) : A new tool to improve headache care].

To enable state-of-the-art diagnosis, therapy and monitoring of headache disorders, comprehensive history taking is necessary and can be time-consuming. This is facilitated substantially if the patient gathers the needed information […]

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Review of mesenchymal stem cell-derived exosomes and their potential therapeutic roles in treating rheumatoid arthritis.

Mesenchymal stem cells (MSCs), one of the most significant categories of stem cells, have garnered considerable attention for their potential in disease treatment due to their unique regenerative properties. MSCs […]

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Global trends in analgesic opioid use in pregnancy: A retrospective cohort study.

Pain is common during pregnancy yet there are few contemporary studies of opioid utilisation in pregnancy. We aimed to describe prescription analgesic opioid use during pregnancy across four regions: Oceania […]

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On the role of psychological and social factors in pharmacological analgesia: A psychosocial moderation hypothesis.

Identifying safe and efficient pharmaceutical pain treatments remains an enduring challenge. However, despite significant advancements in pharmacological pain management, the inconsistent effectiveness of many analgesics between people remains puzzling. To […]

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