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Gender differences in patient experience in idiopathic inflammatory myopathies: Sub analysis from the COVAD dataset.

We aimed to investigate gender-based differences in idiopathic inflammatory myopathies (IIMs), with a particular focus on patient-reported outcomes, utilizing data obtained through the international COVID-19 vaccination in autoimmune disease (COVAD) […]

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Sexual differences in locus coeruleus neurons and related behavior in C57BL/6J mice.

In addition to social and cultural factors, sex differences in the central nervous system have a critical influence on behavior, although the neurobiology underlying these differences remains unclear. Interestingly, the […]

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A Group-Based Intervention to Reduce Opioid Use for Chronic Pain.

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Rab11a in the spinal cord: an essential contributor to complete Freund’s adjuvant-induced inflammatory pain in mice.

Inflammatory pain is a commonly observed clinical symptom in a range of acute and chronic diseases. However, the mechanism of inflammatory pain is far from clear yet. Rab11a, a small […]

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A Group-Based Intervention to Reduce Opioid Use for Chronic Pain-Reply.

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The role of acid-sensing ion channels in monosodium urate-induced gouty pain in mice.

Acid-sensing ion channels (ASICs) in dorsal root ganglion (DRG) neurons play an important role in inflammatory pain. The objective of this study is to observe the regulatory role of ASICs […]

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The effect of preemptive magnesium sulfate on postoperative pain in patients undergoing mastectomy: a clinical trial.

The effects of preemptive magnesium sulfate (MgSO4) infusion on perioperative hemodynamics and postoperative analgesia in female patients who underwent mastectomy were evaluated.

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d-Amino acids: new clinical pathways for brain diseases.

Free d-amino acids (d-AAs) are emerging as a novel and important class of signaling molecules in many organs, including the brain and endocrine systems. There has been considerable progress in […]

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Filaggrin and Beyond: New Insights into the Skin Barrier in Atopic Dermatitis and Allergic Diseases, From Genetics to Therapeutic Perspectives.

Atopic dermatitis is the most common inflammatory skin disease worldwide, affecting 20% of children and 5% of adults. One critical component in the pathophysiology of atopic dermatitis is the epidermal […]

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Sensing the body matters: profiles of interoceptive sensibility in chronic pain adjustment.

Interoception is critical to health regulation and is often disrupted in individuals with chronic pain (ICPs). Interoceptive sensibility (IS)-the self-reported experience and relationship toward internal states-includes skills such as sensing, […]

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