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The German adaptation of the Amputee Body Image Scale and the importance of psychosocial adjustment to prosthesis use.

Negative cognitions related to one’s own body, here referred to as body image disturbances (BID), are common after lower limb amputation and correlate with weak psychological functioning. The Amputee Body […]

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Chronic chemotherapy-induced peripheral neuropathy and pain following paclitaxel versus docetaxel in breast cancer survivors: A cross-sectional study.

Chemotherapy-induced peripheral neuropathy (CIPN) is a concerning late effect of taxane treatment. This study aimed to explore and compare long-term symptoms and consequences of CIPN after docetaxel and paclitaxel treatment. […]

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Antidepressants to Manage Osteoarthritic Pain: The Value of Pain Phenotyping.

Osteoarthritis (OA) is a chronic condition in which pain significantly affects quality of life, often leading to reduced physical activity and disability. Globally, an estimated 595 million people are affected, […]

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The role of nerve transfers in chronic nerve compression syndromes.

Compression neuropathy is a common problem that results in impaired axonal conduction, and with time, numbness, tingling and weakness from muscle atrophy. Supercharge reverse end-to-side (SETS) nerve transfers have emerged […]

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P2Y12-mediated HIV gp120 and ddC-induced neuropathic pain improved by esculin.

We studied whether esculin (ES) has the effect of alleviating peripheral neuropathic pain (NP) in rat models of HIV glycoprotein 120 (gp120) together with zalcitabine (2′,3′-dideoxycytidine; ddC) treatment and explored […]

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Multimodal abnormalities of brain function in chronic low back pain: a systematic review and meta-analysis of neuroimaging studies.

Neuroimaging investigations into chronic low back pain (CLBP) have detected functional abnormalities across a spectrum of brain regions, yet the findings have often been inconsistent. In this meta-analysis, we integrated […]

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Bridging Gaps in Pain Management: The Effectiveness of Educational Intervention for Nurses in a Teaching Hospital of Low- and Middle-Income Countries.

Regular on-the-job training and educational courses may improve nurses’ knowledge and practice regarding pain assessment and initial treatment. To assess the impact of a newly developed educational course in terms […]

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Intradermally injected abobotulinumtoxinA administered preemptively before surgery alleviates post-surgical pain and normalizes behavior in a translational animal model.

Previously, abobotulinumtoxinA (aboBoNT-A) injected intraoperatively resulted in effective, but delayed post-surgical analgesia in pigs. Here, we explore the efficacy of preemptively administered aboBoNT-A in intact animals on pain and associated […]

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Activation of K channels in pain modulation: a systematic review of preclinical studies.

To systematically review the involvement of K channel activation in pain modulation in preclinical studies.

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Intra-somatosensory cortical circuits mediating pain-induced analgesia.

Pain in one part of the body profoundly diminishes the sensation of pain in other parts of the body in humans. Here, we found that pain-related behaviors in hindpaw are […]

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