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Addressing Pain and Heavy Drinking among Patients in HIV-Care: A Pilot Study of an Integrated Telehealth Intervention.

Chronic pain is common among people living with HIV (PLWH) who engage in heavy drinking and both pain and heavy drinking influence quality of life, functioning, and HIV-outcomes. The purpose […]

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Review: An Update on CGRP Monoclonal Antibodies for the Preventive Treatment of Episodic Migraine.

CGRP targeting therapies have revolutionized the migraine preventive space, introducing novel migraine-specific therapies to improve headache care. Four monoclonal antibodies (mAbs) are approved for use in prevention of episodic migraines. […]

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Assessing the Relationship Between Chronic Pain and Cognition: A NIDILRR and VA TBI Model Systems Collaborative Project.

To investigate the associations between current chronic pain and cognition and current chronic head pain and cognition in individuals with traumatic brain injury (TBI).

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Mechanisms of comorbidity between Alzheimer’s disease and pain.

Clinical studies have revealed a significant correlation between pain and neurodegenerative diseases, particularly Alzheimer’s disease (AD). However, due to cognitive and speech impairments, AD patients, especially those in moderate to […]

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Effectiveness of Scolopendrid Pharmacopuncture for Neuropathic Dysfunction: Clinical Evidence and Potential Mechanism.

Animal venoms, particularly venom, have gained significant attention as therapeutic agents in complementary and alternative medicine, especially for applications in pain management and neuroprotection. In traditional Korean medicine, venom is […]

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Opioid-induced neuroanatomical, microglial and behavioral changes are blocked by suvorexant without diminishing opioid analgesia.

Heroin use disorder in humans and chronic opioid administration to mice result in an increase in the number and a decrease in the size of detected hypocretin (Hcrt, or orexin) […]

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Neurotoxins Acting on TRPV1-Building a Molecular Template for the Study of Pain and Thermal Dysfunctions.

Transient Receptor Potential (TRP) channels are ubiquitous proteins involved in a wide range of physiological functions. Some of them are expressed in nociceptors and play a major role in the […]

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TNF-α Enhanced Activity of Sympathetic Neurons in Superior Cervical Ganglion to Promote Chronic Sleep Deprivation-Related Hyperalgesia.

The mechanisms underlying the association between sleep deprivation (SD) and hyperalgesia remain incompletely understood. In this study, the Modified Horizontal Platform Method was employed to induce chronic SD. Neuropathic pain […]

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Lasmiditan and Different Triptans in Menstrual Migraine: A Bayesian Network Meta-analysis.

Menstrual migraine (MM) is a common subtype of migraine that greatly affects a woman’s quality of life. A number of different drugs are used to treat menstrual migraine, but it […]

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Exploring the complexities of chronic pain: The ICEPAIN study on prevalence, lifestyle factors, and quality of life in a general population.

The ICEPAIN study is a longitudinal research project focused on building an extensive database on health-related quality of life (HRQoL), lifestyle, and pain among the general population in Iceland. The […]

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