I am a
Home I AM A Search Login

Accepted

Share this

Cannabis use and illicit opioid cessation among people who use drugs living with chronic pain.

Amidst the opioid overdose crisis, there is interest in cannabis use for pain management and harm reduction. We investigated the relationship between cannabis use and cessation of unregulated opioid use […]

Learn More >

Effects of Acceptance and Commitment Therapy plus Exercise for Older Adults with Chronic Low Back Pain: A Preliminary Cluster Randomized Controlled Trial with Qualitative Interviews.

Chronic low back pain (CLBP) is increasingly prevalent in older adults and often leads to functional disability and depressive symptoms. This 2-arm, double-blinded, pilot cluster RCT, with semi-structured interviews, aimed […]

Learn More >

Nanostructured lipid carriers in Rheumatoid Arthritis: treatment, advancements and applications.

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints and causes pain, swelling, and deformity. Current treatments, including nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs, […]

Learn More >

Notopterol mitigates osteoarthritis progression and relieves pain in mice by inhibiting PI3K/Akt/GPX4-mediated ferroptosis.

Ferroptosis-induced lipid peroxidation in chondrocytes exacerbates intra-articular inflammation, oxidative stress, and articular cartilage degradation, accelerating osteoarthritis (OA) progression. Effective anti-inflammatory and antioxidant interventions can alleviate both joint pain and cartilage […]

Learn More >

Follistatin, A Novel Therapeutic Target for Chronic Pain.

Learn More >

Baseline Functional Connectivity of the Mesolimbic, Salience, and Sensorimotor Systems Predicts Responses to Psychological Therapies for Chronic Low Back Pain With Comorbid Depression: A Functional MRI Study.

Chronic low back pain (CLBP) is a prevalent and debilitating condition. Cognitive behavioral therapy (CBT) can improve coping mechanisms for CLBP and pain-related outcomes. However, the mechanisms by which they […]

Learn More >

Modulating neuroplasticity for chronic pain relief: noninvasive neuromodulation as a promising approach.

Chronic neuropathic pain is a debilitating neuroplastic disorder that notably impacts the quality of life of millions of people worldwide. This complex condition, encompassing various manifestations, such as sciatica, diabetic […]

Learn More >

Clinical Application of Intelligent Pain Management Program in Patients With Postherpetic Neuralgia Patients.

Effective pain management is crucial for treating and caring for individuals with postherpetic neuralgia (PHN). A systematic pain management program for this condition has not been established.

Learn More >

Decoding the mechanism of proanthocyanidins in central analgesia: redox regulation and KCNK3 blockade.

Neuropathic pain causes enduring physical discomfort and emotional distress. Conventional pharmacological treatments often provide restricted relief and may result in undesirable side effects, posing a substantial clinical challenge. Peripheral and […]

Learn More >

Antipruritic Effects of Single Administration of Paroxetine on Acute and Chronic Itch.

Itch is described as an unpleasant sensation, and chronic itch, such as that in atopic dermatitis (AD), often decreases a patient’s QOL. There are few effective treatments for various chronic […]

Learn More >

Search