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An Emerging Perspective on the Role of Fascia in Complex Regional Pain Syndrome: A Narrative Review.
Complex Regional Pain Syndrome (CRPS) is a debilitating pain disorder involving chronic inflammation, neural sensitization and autonomic dysfunction. Fascia, a highly innervated connective tissue, is increasingly recognized for its role […]
Learn More >Complex regional pain syndrome (CRPS) is an idiopathic, highly debilitating chronic disorder with persistent regional pain accompanied by a combination of sensory, motor, and autonomic abnormalities. It is not only […]
Learn More >Postoperative pain is a prevalent problem, often lasting from days to years. To minimize opioid use and associated risks of dependency, Enhanced Recovery After Surgery (ERAS) protocols increasingly incorporate multimodal […]
Learn More >Endometriosis is a complex gynecological disorder characterized by endometrial-like tissue growing outside the uterus, leading to chronic pain, infertility, and reduced quality of life. Its pathophysiology involves genetic, epigenetic, immune, […]
Learn More >Chronic pain inequities follow a social power-driven gradient of health, whereby those with less social advantage experience chronic pain more often. Feeling socially supported may reduce the burden of chronic […]
Learn More >Diabetes mellitus (DM), herpes zoster (HZ) and its sequelae, post-herpetic neuralgia (PHN), are common in elderly individuals. Previous observational studies have shown that the prevalence of HZ and PHN in […]
Learn More >Conditioned pain modulation (CPM) is considered a human proxy for descending inhibitory pain pathways. However, there is wide variation in the CPM response described in the literature and ongoing debate […]
Learn More >Borderline Personality Disorder (BPD) is often linked to self-injurious behaviors, with many patients experiencing decreased pain sensitivity or analgesia during these episodes. In this work, we have shifted the theoretical […]
Learn More >Matrix metalloproteinases (MMPs) cleave proteins of extracellular matrix thus facilitating cellular invasion and cancer progression. High MMP-2 activity is frequently reported in several diseases including endometriosis and cancer. Endometriosis, though […]
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