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The Role of Mast Cells in the Development and Advancement of Endometriosis.

Endometriosis is a medical condition identified by the presence of endometrium-like tissue outside the uterus. This condition is known to result in symptoms such as frequent pelvic pain, infertility, and […]

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Towards opioid access without excess.

A decade after World Health Assembly Resolution 67.19 recognised palliative care as a component of comprehensive care and universal health coverage throughout the life course, a balanced approach to opioid […]

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Unveiling the effects of oligosaccharide liposome on neuropathic pain and motor dysfunction following spinal cord injury in rats: relevance to its antioxidative effects.

Spinal cord injury (SCI) is a leading cause of sensorimotor disorders, impacting millions of people globally. The absence of effective treatments and the side effects of existing medications highlight the […]

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Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice.

Kappa opioid receptor agonists are clinically used to treat pruritis and have therapeutic potential for the treatment of pain and neuropsychiatric disorders. We have previously shown that triazole 1.1 is […]

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A narrative review of autophagy in migraine.

Autophagy is a natural process regulated by autophagy-related genes in eukaryotic cells that involves the degradation of cytoplasmic proteins and old or damaged organelles via the lysosomal pathway to help […]

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The brain-gut axis and chronic pain: mechanisms and therapeutic opportunities.

The brain-gut axis (BGA) is emerging as a critical mediator in chronic pain, involving bidirectional communication between the central nervous system and the gastrointestinal system. The “Pain Matrix” is associated […]

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A Review of Nonsurgical Neurolytic Procedures for Neuropathic Pain.

Ideally, a physical or chemical nonsurgical neurolytic procedure provides targeted neurolysis to relieve pain for a suitable length of time without causing complications. This narrative review focuses on five nonsurgical […]

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Abuse-deterrent wearable device with potential for extended delivery of opioid drugs.

Unethical attempts to misuse and overdose opioids have led to strict prescription limits, necessitating frequent hospital visits and prescriptions for long-term severe pain management. Therefore, this study aimed to develop […]

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Evaluation of long-term outcomes with intrathecal opioid treatment: a comparison utilizing data derived from pain clinic populations in Australia and New Zealand.

An obstacle to analysis of the long-term effectiveness of intrathecal (IT) opioids is absence of historical patient baseline data. The electronic Persistent Pain Outcomes Collaboration (ePPOC) is an initiative of […]

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A Bibliometric and Visual Analysis of Oliceridine Research (2013-2024).

To explore and analyze the current research progress, hotspots, and future trends in oliceridine research using bibliometric methods.

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