Accepted

Neuronal signals have emerged as critical factors that regulate group 3 innate lymphoid cell (ILC3) response and tissue homeostasis, but the molecular mechanisms underlying this regulation remain largely elusive. Here, […]

Intervertebral disc degeneration (IDD) process is accompanied by overactive inflammation and mechanical instability of the nucleus pulposus (NP). Current treatments do not fully restore the biomechanical environment of discs, limiting […]

To determine the causal relationship between multisite chronic pain (MCP) and post-traumatic stress disorder (PTSD) using Mendelian Randomization (MR) analysis. Genome-wide summary statistics for MCP and PTSD were obtained. Linkage […]

Chronic pain is associated with persistent alterations in brain structure and function. However, existing research has not fully explored the relationship between brain network topological properties and clinical symptoms in […]

Habituation to painful stimuli reflects an endogenous pain alleviation mechanism, and reduced pain habituation has been demonstrated in many chronic pain conditions. In ethology, animals exhibit reduced fear responses while […]

To compare the effects of deinorgestrel and Guizhi Fuling Capsules on ovarian function, inflammatory variables, and the rate of conception in clients receiving endometriosis treatment.

The brain is key in the pain-sleep relationship, and sleep is needed for glymphatic clearance. However, no studies have examined how pain relates to the glymphatic system (GS). Characterizing the […]

Diagnosing pain in research and clinical practices still relies on self-report. This study aims to develop an automatic approach that works on resting-state raw EEG data for chronic knee pain […]

Migraine is the most common neurological disorder and the second most disabling human condition. Autotaxin (ATX) is a plasma enzyme that leads to the formation of lysophosphatidic acid (LPA), which […]

Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we […]