Browse by Audience
Pain independent of disease activity is frequently reported by rheumatoid arthritis patients and remains undertreated. Preclinical evidence suggests that imbalance of neuroimmune proresolving interactions within dorsal root ganglia (DRG) rather […]
Learn More >The primary aim of this study was to examine the way in which parent stress, including adverse childhood experiences (ACEs) and emotional distress, pain, and resilience, relates to child pain […]
Learn More >Chronic pain affects millions worldwide, reducing quality of life and posing a major healthcare challenge. This review aims to explore advancements in neurosurgical interventions for managing chronic pain, focusing on […]
Learn More >A subset of peripheral sensory neurons expressing specific Mas-related G-protein-coupled receptors and transient receptor potential channels mediate pruritogen-induced chemical itch. However, the molecular mechanisms that regulate the excitability of these […]
Learn More >Neuropathic pain is a common and severe type of chronic pain, and its pathogenesis has not been fully defined. Increasing evidence shows that spinal astrocytes play indispensable roles in the […]
Learn More >Chronic non-specific low back pain (CNLBP) is a common condition, defined as pain lasting more than 3 months between the lower thoracic margin and gluteal folds, without identifiable tissue damage. Despite […]
Learn More >Raised intracranial pressure (ICP) is associated with altered cerebral hemodynamics and cephalic pain. The relationship between the algetic response and cortical neurovascular changes in raised ICP is unclear. This study […]
Learn More >Chronic pain is a major cause of suffering. This interferes with daily functioning and is often accompanied by distress. However, current therapeutic strategies for chronic pain are unsatisfactory because of […]
Learn More >Mapping the migraine: Intracranial recording of cortical spreading depression in migraine with aura.
Migraine with aura is a common neurological disorder. Cortical spreading depression is the hypothetical pathophysiologic correlate, but it has never been directly recorded during migraine in a human. A 32-year-old […]
Learn More >To examine the most common patterns of pain and symptom management strategies among adults living with cerebral palsy (CP), and to determine if there are differences by pain phenotype or […]
Learn More >