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Metabolomics integrated with mass spectrometry imaging reveals novel action of tetramethylpyrazine in migraine.

Migraine as a common neurological disorder still lacks effective therapies. Tetramethylpyrazine (TMP) is the main bioactive component from Ligusticum chuanxiong hort., a traditional edible-medicinal herb. This study aimed to investigate […]

Assaying Nociception Behaviors in Drosophila Larvae During Parasitoid Wasp Attacks.

Nociception in fruit fly () larvae is characterized by a stereotyped escape behavior. When a larva encounters a noxious (potentially harmful) stimulus, it responds by curving its body into a […]

Mirogabalin: a novel gabapentinoid or another false dawn?

Mirogabalin is a novel gabapentinoid medication for the treatment of neuropathic pain. The purpose of this review is to discuss current evidence for its use. Gabapentinoids are widely prescribed for […]

Mechanical Nociception Assay in Drosophila Larvae.

The nervous system of animals can sense and respond to noxious stimuli, which include noxious thermal, chemical, or mechanical stimuli, through a process called nociception. Here, we describe a simple […]

The Interplay Between Health Disparities and Acceptability of Virtual Reality: A Survey Study.

Virtual reality (VR) has emerged as a nonpharmacological adjuvant to manage acute and chronic pain symptoms. The goal of this survey study was to determine the acceptability of VR among […]

Nociception in Drosophila Larvae.

Nociception is the sensory modality by which animals sense stimuli associated with injury or potential tissue damage. When larvae encounter a noxious thermal, chemical, or mechanical stimulus, they perform a […]

Evaluation of Online Large Language Models for Patient Education Regarding Chronic Low Back Pain.

Heeding Pain’s Prescription.

Newer definitions of pain remain suggestive of categorization by mainly neurological or psychological bases. All pain recruits cortical interpretation for any sort of directive effects in awareness, attention, and action. […]

Trainee Insight into Pain Fellowship Programs: A Critical Evaluation of the Current Educational System by the APPD.

Since 1992, when the Accreditation Council of Graduate Medical Education (ACGME) acknowledged pain medicine as a subspecialty, the field has experienced significant growth in its number of programs, diversity of […]

Headache-related disability as a function of migraine aura: A daily diary study.

To examine the unique role of migraine aura in predicting day-to-day levels of headache-related disability.

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