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Deciphering distinct spatial alterations in N-glycan expression profiles in the spinal cord and brain of male rats in a neuropathic pain model.

Neuropathic pain is a complex condition resulting from damage or disease in the somatosensory nervous system, causing significant physical and emotional distress. Despite its profound impact, the underlying causes and […]

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A glutamatergic innervation from medial area of secondary visual cortex to lateral posterior thalamic nucleus facilitates nociceptive and neuropathic pain.

Neuropathic pain involves complex cortical mechanisms, yet the role of the medial secondary visual cortex (V2M) remains poorly understood. We hypothesized that glutamatergic neurons in V2M (V2M) contribute to pain […]

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Monkeys increase scratching when encountering unexpected good fortune.

Elucidating how ancestral behavioural traits have been repurposed for psychological and social functions is critical to advancing our understanding of human behavioural evolution. Self-scratching, originally a hygienic response and known […]

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Estradiol protects against pain-facilitated fentanyl use via suppression of opioid-evoked dopamine activity in males.

Pain relief is the most frequently reported motivation for opioid misuse, but it remains unclear how pain alters reward pathway function contributing to maladaptive opioid use and whether these neuroadaptations […]

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Convergent validity of 12-item World Health Organization Disability Assessment Schedule (WHODAS 2.0) among people with neck pain.

To explore the convergent validity of 12-item World Health Organization Disability Assessment Schedule (WHODAS 2.0) comparing it to Neck Disability Index (NDI).

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Virtual reality for menopause symptom management: opportunities, challenges, and next steps.

Menopause is the natural cessation of ovarian function, typically occurring at a mean age of 52 years in the United States. Vasomotor symptoms (VMS; hot flashes and night sweats) affect […]

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Exploring Immune-Related Biomarkers in Human Itch.

Itch is a debilitating symptom that affects ∼40% of the population and significantly impacts patients’ quality of life. The management of chronic itch remains a significant challenge due to the […]

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The burden of migraine in Mexico: a database analysis of migraine-related visits to emergency departments in Mexico’s ministry of health (MMoH) hospitals.

The burden of migraine in Mexican Emergency Department (ED) settings remains understudied. This study aimed to determine the frequency of migraine-related ED visits within the ED Mexican Ministry of Health’s […]

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Consensus statement on pain management for pregnant patients with opioid use disorder from the Society for Obstetric Anesthesia and Perinatology, Society for Maternal-Fetal Medicine, and American Society of Regional Anesthesia and Pain Medicine.

Pain management in pregnant and postpartum people with an opioid use disorder requires a balance among the risks associated with opioid tolerance, including withdrawal or return to opioid use, considerations […]

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Effects of ozone treatment on chemotherapy-induced peripheral neuropathy: a promising research area.

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