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Does Leptin and Insulin Levels Influence Pain and Disability in Subjects With Frozen Shoulder? A Cross-Sectional Study.

To investigate the relationship between leptin levels, insulin resistance (measured by HOMA), and clinical outcomes related to pain, disability, and shoulder range of motion (ROM) in patients with frozen shoulder […]

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Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape.

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Development of a Novel 11-Gene Signature Related to Immune Subtypes for Fibromyalgia.

The purpose of this study was to identify molecular subtypes and hub genes in fibromyalgia [FM] based on immune-related genes [IRGs].

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Risk of Cannabis Use Disorder in Chronic Pain: Longitudinal Links to Pain Outcomes.

The aim of this study was to compare individuals with chronic pain who were cannabis nonusers and those at low, moderate, and high cannabis use disorder (CUD) risk levels on […]

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Managing Opioid Tolerance: Balancing Pain Relief and Tackling Addiction.

This editorial discusses opioid tolerance, a growing challenge in managing pain in chronic patients. With time, overuse of opioids causes less sensitivity and responsiveness of opioid receptors and leads to […]

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Headache characteristics in acromegaly: Only a secondary disorder?

To investigate the characteristics and nature of headache in a population of patients with acromegaly.

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Incidence of chronic postsurgical pain after caesarean delivery: a systematic review and meta-analysis.

Chronic postsurgical pain is recognised increasingly as a complication of caesarean delivery, with implications for a large cohort of patients. As interest in this area has grown, there has been […]

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Machine learning models and classification algorithms in the diagnosis of vestibular migraine: A systematic review and meta-analysis.

To perform a systematic review and meta-analysis to evaluate the effectiveness of machine learning (ML) algorithms in the diagnosis of vestibular migraine.

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Part I: understanding pain in pigs-basic knowledge about pain assessment, measures and therapy.

Pigs can suffer from pain due to spontaneously occurring diseases, wounds, injuries, trauma, and physiological conditions such as the farrowing process; however, this pain is often neglected. To increase knowledge […]

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Abnormal Functional Network Centrality and Causal Connectivity in Migraine Without Aura: A Resting-State fMRI Study.

The pathophysiological mechanism of migraine is still not clear. Thus, this study aimed to evaluate the changes in effective connectivity (EC) in the brain functional network underlying migraine and its […]

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