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Structural brain alterations and changes in resting-state functional connectivity in patients with trigeminal neuralgia: A meta-analysis.

Trigeminal neuralgia (TN) is a chronic pain condition characterized by severe, electric shock-like pain in one or more branches of the trigeminal nerve. Even though neuroimaging studies have highlighted alterations […]

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Fibrosis of the infrapatellar fat pad induces gradual cartilage degeneration in a rat model.

Knee osteoarthritis (OA), a degenerative joint disease, causes pain and reduced activity levels, with prevalence increasing with age. Knee OA is recognized as a “joint organ disease,” where interactions between […]

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Lubrication for Osteoarthritis: From Single-Function to Multifunctional Lubricants.

Osteoarthritis (OA) is a common degenerative joint disease that progressively destroys articular cartilage, leading to increased joint friction and severe pain. Therefore, OA can be treated by restoring the lubricating […]

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Systemic Administration of the Phytochemical, Myricetin, Attenuates the Excitability of Rat Nociceptive Secondary Trigeminal Neurons.

While the modulation of the excitatory and inhibitory neuronal transmission by the phytochemical flavonoid, myricetin (MYR), has been noted in the nervous system, the way in which MYR affects the […]

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Endometriosis in Adolescence: A Narrative Review of the Psychological and Clinical Implications.

Endometriosis is a chronic, inflammatory condition where endometrial-like tissue grows outside the uterus, affecting around 10% of women of reproductive age. This condition is associated with debilitating symptoms, including dysmenorrhea, […]

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Stigmatizing attitudes toward people with migraine by people without active migraine: results of the OVERCOME (US) study.

Migraine is associated with various types of stigma. This study aims to evaluate stigmatizing attitudes towards people with migraine by people without active migraine.

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Headache types and characteristics in patients with Amyotrophic Lateral Sclerosis.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder associated with progressive loss of motor neurons, this result in muscle denervation, atrophy and consequently death takes place due to respiratory […]

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Temporomandibular disorders and mental health: shared etiologies and treatment approaches.

The biopsychosocial model suggests that temporomandibular disorders (TMDs) often coexist with mental health disorders, particularly depression and anxiety, affecting a significant portion of the global population. The interplay between TMDs […]

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The characteristics of brain function alterations in patients with chronic prostatitis/chronic pelvic pain syndrome across varying symptom severities evaluated by NIH-CPSI.

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent condition in urology characterized by chronic pain. The pathogenesis of CP/CPPS remains unclear.

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Identification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women.

Patients with Complex Regional Pain Syndrome (CRPS) present prolonged, debilitating pain and functional impairment. Treatments are not disease-modifying due to the poorly understood underlying pathomechanisms. This study aimed to identify […]

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