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Fibromyalgia and Rehabilitation. Not as You Thought. Changing the Stigma.

A cohort of patients in the rehabilitation wards also suffer from Fibromyalgia, which is considered the most prevalent cause of chronic pain. Poor function, subjective cognitive impairment, instability and imbalance […]

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Neuroimaging differences between chronic migraine with and without medication overuse headache: a 7 Tesla multimodal MRI study.

Chronic migraine (CM) patients with medication overuse headache (MOH) exhibit distinct neurobiological alterations compared to those without MOH. However, prior studies, often limited to single imaging modalities, have yielded inconsistent […]

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Rates and risk factors for migraine progression using multiple definitions of progression: Results of the longitudinal OVERCOME (US) study.

To estimate rates of migraine progression and assess predictors of progression in a large, longitudinal cohort study using the traditional definition and two alternative definitions of migraine progression.

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Colitis can reduce the cingulate cortex neuronal density in rats.

Hyperalgesia and hypersensitivity in patients with Inflammatory Bowel Disease (IBD) can be related to central nervous system (CNS) changes, particularly in the pain pathways. The objective of this study was […]

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Efficacy of an educational website on headaches in schoolchildren: A cluster-randomized controlled trial.

In this cluster-randomized controlled trial, we developed an educational website on tension-type headache and migraine for children and adolescents and evaluated its effectiveness in a school setting.

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Dysregulation of MicroRNA Biogenesis Machinery in Nervous System Diseases.

MicroRNAs (miRNAs) have become essential modulators in many brain disorders, such as neurodegenerative diseases, psychiatry disorders, and chronic pain syndromes, and they play a critical role in controlling gene expression. […]

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Hidden headache hero: Dr. Bernice Grafstein, cortical spreading depolarization, and the advancement of women in neuroscience.

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Explaining trunk strength variation and improvement following resistance training in people with chronic low back pain: clinical and performance-based outcomes analysis.

A multitude of variables contribute to the variation of trunk strength in individuals with chronic low back pain (CLBP). This study investigated a range of variables to determine which variables […]

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Assessing blood pressure changes and hypertension-related outcomes in patients with migraine treated with erenumab: A systematic review and meta-analysis.

We aimed to systematically review and summarize evidence on the effects of erenumab on systemic blood pressure (BP) in patients with migraine (International Prospective Register of Systematic Reviews ID: CRD42024571056). […]

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Structure-guided design of partial agonists at an opioid receptor.

Chronic pain and opioid overdose deaths highlight the need for non-addictive analgesics with novel mechanisms. The δ opioid receptor (δOR) is a promising target, as it lacks the respiratory depression […]

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