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Virtual Reality Combined with Mind-Body Therapies for the Management of Pain: A Scoping Review.

When used separately, virtual reality (VR) and mind-body therapies (MBTs) have the potential to reduce pain across various acute and chronic conditions. While their combination is increasingly used, no study […]

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Editorial: Molecular neurobiology of chronic pain: pharmacological and non-pharmacological approaches in animal models.

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Machine learning and biological validation identify sphingolipids as potential mediators of paclitaxel-induced neuropathy in cancer patients.

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious therapy-limiting side effect of commonly used anticancer drugs. Previous studies suggest that lipids may play a role in CIPN. Therefore, the present study […]

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A stacked machine learning-based classification model for endometriosis and adenomyosis: a retrospective cohort study utilizing peripheral blood and coagulation markers.

Endometriosis (EMs) and adenomyosis (AD) are common gynecological diseases that impact women’s health, and they share symptoms such as dysmenorrhea, chronic pain, and infertility, which adversely affect women’s quality of […]

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Pathology and physiology of acid-sensitive ion channels in the bladder.

Acid-sensitive ion channels (ASICs) are sodium-permeable channels activated by extracellular acidification. They can be activated and trigger the inward flow of Na when the extracellular environment is acidic, leading to […]

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Behavioral video coding analysis of chronic morphine administration in rats.

The present study assessed the behavior of morphine-addicted rats using behavioral video coding technology, to evaluate effective methods for identifying morphine addiction. Rats were divided into a control group (n=15) […]

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Physicians’ Self-Reported Knowledge and Behaviors Related to Prescribing Opioids for Chronic Pain and Diagnosing Opioid Use Disorder, DocStyles, 2020.

In 2016, the Centers for Disease Control and Prevention released the Guideline for Prescribing Opioids for Chronic Pain (2016 Centers for Disease Control and Prevention Guideline) to improve opioid prescribing […]

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Cytokines reprogram airway sensory neurons in asthma.

Nociceptor neurons play a crucial role in maintaining the body’s homeostasis by detecting and responding to potential dangers in the environment. However, this function can be detrimental during allergic reactions, […]

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Decoding polyubiquitin regulation of K 7. 1 functional expression with engineered linkage-selective deubiquitinases.

Protein posttranslational modification with distinct polyubiquitin linkage chains is a critical component of the ‘ubiquitin code’ that universally regulates protein expression and function to control biology. Functional consequences of diverse […]

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Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice.

Temporomandibular joint (TMJ) pain and osteoarthritis (OA) are common and debilitating disorders that impair patients’ quality of life. The mechanisms driving diseases-related pain are poorly understood, and current treatments fail […]

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