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Previous studies suggest higher mindfulness may be associated with better sleep quality in people with chronic pain conditions. However, the relationship between mindfulness and sleep in fibromyalgia patients, who commonly suffer from sleep problems, remains unstudied. We examined the relationship between mindfulness and sleep, and how this relationship may be mediated by depression, anxiety, and pain interference in fibromyalgia patients.
Learn More >Unrelieved cancer pain at the end of life interferes with achieving patient-centered goals.
Learn More >Migraine is a heterogeneous condition with multiple clinical manifestations. Machine-learning algorithms permit the identification of population groups providing analytical advantages over other modeling techniques.
Learn More >To investigate the temporal changes of circadian rhythmicity in relation to the disease course in patients with cluster headache.
Learn More >This Review summarises recent pharmacological and upcoming alternative interventions for children with functional abdominal pain disorders (FAPDs). Pharmacological targets include prokinetics and drugs affecting gastric accommodation to treat postprandial distress and nausea. Similarly, anti-inflammatory agents, junctional protein regulators, analgesics, secretagogues, and serotonin antagonists have a therapeutic role for irritable bowel syndrome. Non-pharmacological treatments include peripheral electrical nerve field stimulation to the external ear, gastric electrical stimulation, dietary interventions such as low fructose and fibre based diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics. Newer psychological advances such as exposure-based cognitive behavioural therapy, acceptance and commitment therapy, and mindfulness meditation are being investigated for paediatric functional pain. Lastly, alternative therapies such as acupuncture, moxibustion, yoga, and spinal manipulation are also gaining popularity in the treatment of FAPDs.
Learn More >With increasing costs of health care in the United States, attention is focused on expensive conditions. Musculoskeletal disorders with low back and neck pain account for the third highest amount of various disease categories. Minimally invasive interventional techniques for managing spinal pain, including epidural injections, have been considered to be growing rapidly. However, recent analyses of utilization of interventional techniques from 2000 to 2018 has shown a decline of 2.6% and a decline of 21% from 2009 to 2018 for epidural and adhesiolysis procedures.
Learn More >To explore strategies used by people living with chronic pain when participating in physical activity and exercise and their recommendations for health care providers when promoting participation in physical activity and exercise.
Learn More >Pain is a complex and highly subjective phenomenon that can be modulated by several factors. Based on results from experimental and clinical studies, the existence of endogenous pain modulatory mechanisms that can increase or diminish the experience of pain is now accepted. In this narrative review, the pain modulatory effects of exercise, stress, and cognitions in humans are assessed. Experimental studies on the effect of exercise have revealed that pain-free subjects show a hypoalgesic response after exercise. However, in some patients with chronic pain this response is reduced or even hyperalgesic in nature. These findings will be discussed from a mechanistic point of view. Stress is another modulator of the pain experience. Although acute stress may induce hypoalgesia, ongoing clinical stress has detrimental effects on pain in many patients with chronic pain conditions, which have implications for the understanding, assessment and treatment of stress in patients with pain. Finally, cognitive strategies play differing roles in pain inhibition. Two intuitive strategies, thought suppression and focused distraction, will be reviewed regarding experimental, acute, and chronic pain. Based on current knowledge on the role of exercise, stress, and cognitive pain control strategies on modulation of pain, implications for treatment will be discussed.
Learn More >We aimed to examine arterial stiffness and vitamin K2 status in migraine subjects by comparison to controls.
Learn More >Although many national surveys have been published on migraine epidemiology, such as that carried out by Wolfson et al in Canada [1], recent information on global epidemiologic burden of this condition has not been published. Therefore, in this succinct report we present an update on worldwide epidemiology of migraine, based on data retrieved from the official database of the World Health Organization (WHO) [2].
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