Accepted

In the peripheral nervous system, nociceptors become hyperexcitable in both acute and chronic pain conditions. This phenotype can be mediated by dysregulated calcium, which occurs if the endoplasmic reticulum (ER) […]

In the context of vulvodynia, a gynecological disorder characterized by chronic vulvar pain affecting an estimated 10% of women, with significant impacts on sexual health, mental well-being, and productivity, the […]

Early life stress (ELS) is associated with an increased risk of experiencing chronic pain during adulthood, but surprisingly little is known about the short-term influence of ELS on nociceptive processing […]

This study explored diverse care trajectories (CTs) for low back pain (LBP) and other musculoskeletal disorders (MSDs), over a 5-year period following a first episode of LBP. Based on Quebec’s […]

Central nervous system complications are common in sickle cell disease (SCD), and the defining associated biomarkers are becoming increasingly relevant for physicians in diagnostic and prognostic contexts. Recent studies have […]

Menstrual migraine (MM) is a debilitating migraine subtype associated with hormonal fluctuations, often resistant to conventional treatments. Gepants, novel calcitonin generelated peptide (CGRP) receptor antagonists, and ditans, serotonin 5-HT1F receptor […]

The term “mixed pain” is frequently used in clinical practice to describe the coexistence of nociceptive, neuropathic, and nociplastic pain mechanisms. However, its inconsistent use and lack of a formal […]

This study investigates whether data from people with endometriosis (n = 58) and fibromyalgia (n = 58) exhibit what is called “ergodicity,” meaning that results from analyses of aggregated group […]

Chronic widespread pain (CWP)-as in many other clinical presentations-manifests in ongoing pain without identifiable structural cause, with pain that spreads over multiple body areas. The development and maintenance of symptoms […]

Our study aimed to explore the potential of Photobiomodulation (PBM) as a treatment for Tendinopathy (TP), a chronic condition characterized by tendon degeneration, inflammation, and pain, for which current treatment […]