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An excitatory neural circuit for descending inhibition of itch processing.

Itch serves as a self-protection mechanism against harmful external agents, whereas uncontrolled and persistent itch severely influences the quality of life of patients and aggravates their diseases. Unfortunately, the existing […]

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Pain catastrophizing and pain anxiety mediate changes in physical function in a mind-body intervention for adults with traumatic orthopedic injuries.

Traumatic orthopedic injuries are common and frequently associated with persistent pain, disability, and emotional distress. Risk factors of persistent pain and disability include pain catastrophizing and pain anxiety, though most […]

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Predicting chronic post-traumatic head and neck pain: the role of bedside parameters.

Traumatic brain injury (TBI) annually impacts 69 million individuals worldwide. Mild TBI constitutes approximately 90% of all TBIs. Chronic pain post-mTBI occurs in 29% to 58% of patients. This study […]

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The Global Burden of Migraine: A 30-Year Trend Review and Future Projections by Age, Sex, Country, and Region.

Migraine is a prevalent neurological disorder causing significant disability worldwide. Despite extensive research on specific populations, comprehensive analyses of global trends are remains limited.

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Associations between NCLBP, spinal sagittal alignment and age groups: a cross-sectional cohort study.

Nonspecific chronic low back pain (NCLBP) is one of the most common manifestations of degenerative spondylitis. It affects many patients of all ages and seriously interferes with quality of life. […]

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Heterogeneity in Pancreatitis: Recognizing Heterogeneity and Its Role in the Management of Pancreatitis. Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Both the clinical management and study of recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) is complicated by significant heterogeneity in the etiology, mechanisms, symptoms, and complications of pancreatitis. The […]

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Dimming chronic pain with ultrasound: hope for the future?

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Scratching the surface: the complex interface of chronic pain and mental health treatment needs in the United States.

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A study of changes in hematologic parameters in patients with migraine.

To evaluate the characteristics of hematological parameters and peripheral inflammatory markers in migraine, including chronic migraine (CM) and episodic migraine (EM), and to explore their underlying mechanisms.

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Exercise as an abortive treatment for cluster headaches: Insights from a large patient registry.

This study aimed to evaluate the potential of exercise as an abortive treatment for patients with cluster headache (CH).

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