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A Longitudinal Exploration of -Related Hemiplegic Migraine in Children Using Electronic Medical Records.

Since the initial description of related hemiplegic migraine (HM), the phenotypic spectrum has expanded from mild episodes in neurotypical individuals to potentially life-threatening events frequently seen in individuals with developmental […]

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Feasibility of attention-based virtual reality interventions in fibromyalgia syndrome: comparing systems, virtual environments and activities.

Fibromyalgia Syndrome (FMS) is highly prevalent with a significant associated morbidity and socioeconomic burden. Effective treatments for FMS remain elusive with pharmacological management (including use of opioids) often proving ineffective. […]

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Transforming grayscale MRI images to color utilizing generative artificial intelligence to better understand multiple sclerosis.

Multiple sclerosis (MS) falls within the spectrum of central nervous system (CNS) demyelinating diseases that may lead to permanent neurological disability. Fundamental to the diagnosis and clinical surveillance is magnetic […]

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Comprehensive and Efficient Assessment of Psychological Flexibility in the Context of Chronic Pain.

The Multidimensional Psychological Flexibility Inventory (MPFI) is a measure of all facets of psychological flexibility and inflexibility, potentially important processes of change in psychological treatment for chronic pain. In some […]

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Polysaccharide-based biomaterials for regenerative therapy in intervertebral disc degeneration.

Intervertebral disc (IVD) degeneration represents a significant cause of chronic back pain and disability, with a substantial impact on the quality of life. Conventional therapeutic modalities frequently address the symptoms […]

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Melittin as a therapeutic agent for rheumatoid arthritis: mechanistic insights, advanced delivery systems, and future perspectives.

Rheumatoid arthritis (RA), a condition characterized by joint deterioration through the action of matrix metalloproteinases (MMPs), is prevalent worldwide. Bee venom (BV) has traditionally been used in Chinese medicine for […]

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Anti-allodynic effect of intrathecal antibodies against macrophage-inducible C-type lectin in spinal nerve ligation model in rat.

Macrophage-inducible C-type lectin (Mincle) has emerged as a potential contributor to neuropathic pain induction and neuroinflammatory responses within the spinal cord. Moreover, evidence suggests a close association between toll-like receptor […]

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Employer Perspective on Pain Fellowship Education: A Survey to Understand the Current State of Pain Medicine Training.

Pain medicine care has expanded to encompass a wider range of conditions, necessitating updated education and training for pain specialists to utilize emerging technologies effectively. A national survey was conducted […]

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A digital tool for multidimensional assessment and prediction of treatment effectiveness in chronic pain management.

Given the multidimensional aspect of pain, the assessment of treatment efficacy is challenging. The prospective observational multicenter PREDIBACK study aimed to assess, compare, and predict the effectiveness of different treatments […]

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Dynamic fluctuations in brain iron content during migraine attacks: insights from relaxometry and diffusion tensor imaging.

There is evidence that iron metabolism may play a role in the underlying pathophysiological mechanism of migraine. Studies using (=1/ ) relaxometry, a common MRI-based iron mapping technique, have reported […]

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