Accepted

An increase in the use of medicinal Cannabis for pain management has spurred research into the understudied bioactive compounds in Cannabis, such as terpenes. In our previous work, we showed […]

Atypical chemokine receptor 3 (ACKR3) (formerly CXCR7) regulates various biological processes through its ligands and is closely associated with numerous diseases, including inflammation, cancer, cardiovascular diseases (CVDs), pain, and neurological […]

Purpose Up to 40% of long-term cancer survivors suffer from chronic cancer-related pain (CCRP) with often inadequate treatment. CCRP is influenced by biopsychosocial factors, with interdisciplinary multimodal pain therapy (IMPT) […]

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterus, leading to symptoms such as dysmenorrhea and chronic pain. It affects approximately 2-10 % of women […]

Chronic pancreatitis (CP) is characterized by inflammation, acinar cell death, fibrosis, and persistent pain. We investigated mesenchymal stem/stromal cell (MSC)-derived extracellular vesicles (EVs) for CP treatment. CP was modeled in […]

Neuropathic pain (NP) is a chronic and debilitating condition frequently comorbid with insomnia. However, the alterations in sleep architecture under NP conditions and the mechanisms underlying both pain and sleep […]

Infants undergo multiple clinically-required painful procedures during their time in hospital, and there is an increasing desire from both parents and clinical staff to have parents directly involved in their […]

Monocyclic monoterpenoid ocimene (OC) was evaluated as a potential inhibitor of TLR4/NLRP3/GSDMD-driven pyroptosis, implicated in conditions such as chronic pain, inflammation, and gastric ulcers. This study investigated OC’s protective effects […]

Intra-Discal Vacuum phenomenon (IDVP) is associated with advanced disc degeneration, representing persistent intra-segmental movement. Our objective is to further characterise IDVP patterns from both MRI and CT thus informing on […]

Women with endometriosis still have to seek the legitimacy of their disease from the medical community and often feel unheard. This scoping review aims to map the scientific literature to […]