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Neuroscientific underpinnings of psychosocial factors in chronic pain.

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Reversing Neuronal Klotho Dysfunction-Mediated Diabetic Neuropathy Through 16:8 Intermittent Fasting.

Insulin supply is the golden standard for type 1 diabetes mellitus (T1DM) therapy. Is there a drug-reduction application for reversing glucose metabolism disabled and diabetic neuropathy (DN), and is it […]

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Electroacupuncture at 5/100 Hz alleviates neuropathic pain in rats by inhibiting the CCL3/CCR5 axis in the spinal cord.

Typically, neuropathic pain (NP) is difficult to manage as it is refractory to conventional medications. Electroacupuncture (EA) at 5/100 Hz has emerged as an effective and promising treatment for NP; however, […]

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Reviewing Psychological Practices to Enhance the Psychological Resilience Process for Individuals with Chronic Pain: Clinical Implications and Neurocognitive Findings.

Psychological practices have emerged as promising treatments for coping with chronic pain (CP) as a psychological resilience (PR) enhancer mechanism. These practices contain cognitive, behavioral and emotional modulation of pain. […]

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VR-guided exercise and mindfulness program for people with chronic pain: a randomised controlled cross-over pilot trial.

Physical exercises and mindfulness are important components in the management of chronic pain, but pain may reduce exercise adherence. Virtual reality (VR) can provide cognitive inhibition of the ascending pain […]

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Targeted Ganglion Delivery of CaV2.2-Mediated Peptide by DNA Nanoflowers for Relieving Myocardial Infarction and Neuropathic Pain.

N-type calcium channel (CaV2.2) protein contributes to neuronal excitability and overactivation in sympathetic ganglion (SG) following myocardial infarction (MI), thereby easily triggering cardiac remodeling and ventricular arrhythmias (VAs). Despite much […]

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Are there any differences between adult-onset cerebellitis and childhood cerebellitis?

Acute cerebellitis (AC), a rare inflammatory disorder of the cerebellum, is primarily associated with infectious, post-infectious, and autoimmune mechanisms. It predominantly affects children and typically follows a benign and self-limited […]

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An association study of multimodal neuroimage features and gene expression in adolescents with centrally mediated abdominal pain syndrome.

Centrally mediated abdominal pain syndrome (CAPS) is a complex condition characterised by persistent abdominal discomfort in the absence of clear physiological abnormalities. Its aetiology remains poorly understood, but recent research […]

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Taraxasterol attenuates inflammatory responses in a 2,4-dinitrochlorobenzene-induced atopic dermatitis mouse model via inactivation of the MAPK and NF-κB pathways.

Atopic dermatitis (AD) is an inflammatory skin disease. Taraxasterol has anti-inflammatory effects in various pathological processes. In this study, our goal is to detect the biological functions of taraxasterol and […]

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To feel is to heal-introduction to Emotional Awareness and Expression Therapy.

Persistent physical symptoms (PPS), including (primary) pain, can, according to Emotional Awareness and Expression Therapy (EAET), be precipitated, perpetuated, and prolonged by emotional processes related to unresolved trauma and psychosocial […]

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