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A review of current treatments for chronic prostatitis/chronic pelvic pain syndrome under the UPOINTS system.

Prostatitis is classified into four categories according to the National Institutes of Health Consensus Classification. The largest category, Category III chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), has a […]

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PK/PD analysis of trazodone and gabapentin in neuropathic pain rodent models: Translational PK-PD modeling from nonclinical to clinical development.

A pharmacokinetic/pharmacodynamic (PK/PD) model was developed to describe the time course of writhings after intraperitoneal injection of acetic acid in mice. The model was applied to investigate the antinociceptive effect […]

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The role of Na1.9 in the sensory perception of itch.

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A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons.

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Patch clamp study of benzydamine effect over neuronal excitability on inflammation sensitized rat nociceptors.

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Na1.9: A unique voltage-gated sodium channel with a role in inflammatory pain.

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Sensorimotor gating in chronic migraine and its association to bilateral greater occipital nerve block.

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Update on primary headache associated with sexual activity and primary thunderclap headache.

This narrative review aims to provide an update on primary headache associated with sexual activity and primary thunderclap headache.

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Hypnic Headache – What do we know in 2022?

Hypnic Headache, also known as “alarm clock headache”, is a rare primary headache disorder. It is characterized by frequently recurring headache attacks, which only develop during sleep, especially nighttime sleep.

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Effects of insufficient sleep on sensorimotor processing in migraine: A randomised, blinded crossover study of event related beta oscillations.

Migraine has a largely unexplained connection with sleep and is possibly related to a dysfunction of thalamocortical systems and cortical inhibition. In this study we investigate the effect of insufficient […]

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