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Idiopathic intracranial hypertension (IIH) is a disease defined by elevated intracranial pressure (ICP) without an established etiology. Arachnoid granulations (AG) are conduits for CSF resorption from the subarachnoid space to […]
Learn More >Chronic pain is not only one of the most common health problems, it is often challenging to treat adequately. Chronic pain has a high prevalence globally, affecting approximately 20% of […]
Learn More >The mechanisms of change in digital interventions for the prevention of depression are largely unknown. Here, we explored whether five theoretically derived intervening variables (i.e., pain intensity, pain-related disability, pain […]
Learn More >To investigate how a behavioral health, artificial intelligence (AI)-powered, digital self-management tool affects the daily functions in adults with chronic back and neck pain.
Learn More >This systematic review and meta-analysis synthesize the evidence on the prospective bidirectional associations between sleep-related problems (SRP) and chronic musculoskeletal pain (CMP).
Learn More >Chronic pain (CP) is often accompanied by mental disorders (MDs). However, little is known concerning the long-term effect of MDs, personality traits, and early-life traumatic events (ETEs) on CP course. […]
Learn More >Determine the relative effectiveness and safety profiles of percutaneous and minimally invasive interventions for chronic low back pain.
Learn More >Neuropathic pain is a chronic condition that tends to worsen over time, leading to a significant decline in patients’ quality of life. The elderly population is disproportionately affected by this […]
Learn More >(1) Background: Randomized controlled trials and real-life studies demonstrated the efficacy of OnabotulinumtoxinA (OBT-A) for CM prevention. However, no studies specifically addressed its effect on pain’s quantitative intensity and qualitative […]
Learn More >Temporomandibular disorders (TMD) are complex pathologies responsible for chronic orofacial pain. Intramuscular injection of botulinum toxin A (BoNT/A) has shown effectiveness in knee and shoulder osteoarthritis, as well as in […]
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