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The Convergent Validity of Pain Drawings and Anatomical Checklists in Individuals with Chronic Pain.

The assessment of the spatial characteristics of pain, such as location and extent, is essential in the clinical evaluation of pain syndromes, especially when managing patient’s with chronic musculoskeletal pain. […]

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Fear-avoidance beliefs are associated with changes of back shape and function.

Psychosocial function in people with chronic low back pain (cLBP) is often impaired, indicating poor well-being. Fear-avoidance beliefs (FAB) are common concomitants of cLBP. Fear-avoidance beliefs are gaining attention as […]

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Oral pH- and inflammation-targeted delivery system with biodegradable multi-layer core-shell nanocapsules for the treatment of ulcerative colitis.

Most biologics require administration parenteral routes; however, the pain and local allergic reaction brought about by injection usually lead to poor compliance, especially for chronic patients. Meanwhile, the oral delivery […]

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Profiling chronic migraine patients according to clinical characteristics: a cluster analysis approach.

To group the characteristics of chronic migraine (CM) by headache characteristics.

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Melittin: A Promising Therapeutic Agent for Rheumatoid Arthritis Treatment.

Rheumatoid Arthritis (RA) is a globally prevalent chronic disease that presents significant challenges in terms of curability. The etiology and onset of RA are not readily identifiable, and as the […]

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The “brain-gut” mechanism of postherpetic neuralgia: a mini-review.

Postherpetic neuralgia (PHN), a representative type of neuropathic pain, has attracted much research on its diagnosis and therapy at the molecular level. Interestingly, this study based on the brain-gut axis […]

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Dysregulation of lipid metabolism, energy production, and oxidative stress in myalgic encephalomyelitis/chronic fatigue syndrome, Gulf War Syndrome and fibromyalgia.

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Gulf War Syndrome (GWS), and Fibromyalgia (FM) are complex, chronic illnesses with overlapping clinical features. Symptoms that are reported across these conditions include post-exertional malaise […]

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Diagnostic and Management Strategies of Visual Snow Syndrome: Current Perspectives.

Visual Snow Syndrome (VSS) is characterized by the presence of dynamic, continuous, tiny dots in the entire visual field persisting for more than three months, with at least two associated […]

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Amplitude of low-frequency fluctuations in classical trigeminal neuralgia patients with purely paroxysmal and concomitant continuous pain.

Purely paroxysmal neuralgia (PP-CTN) and concomitant continuous pain (CCP-CTN) are different subtypes of classical trigeminal neuralgia (CTN). Our aim was to explore the common and unique spontaneous brain activity abnormalities […]

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Loss of SCRG1 in chondrocytes inhibits osteoarthritis by promoting autophagy activity in the temporomandibular joint through inhibition of neurokine receptors.

To investigate how scrapie responsive gene 1 (SCRG1) contributes to the development of temporomandibular joint osteoarthritis (TMJOA).

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