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Classification of Nanomaterial Drug Delivery Systems for Inflammatory Bowel Disease.

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, primarily arises from defects in the colonic barrier, imbalances of the gut microbiota, and immune response issues. These complex causes […]

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Acupuncture for the prevention of episodic migraine.

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To investigate whether acupuncture is more effective than ‘sham’ (placebo) acupuncture, no preventative treatment or routine […]

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Systemic antihyperalgesic effect of a novel conotoxin from Californiconus californicus in an inflammatory pain model.

This study explores the analgesic potential of the novel conotoxin O1_cal6.4b, derived from Californiconus californicus, as a candidate for pain management in a model of inflammatory pain.

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Association between obstructive sleep apnea and migraine: A United States population-based cohort study.

To determine the association between obstructive sleep apnea (OSA) and the incidence of migraine using a large population-based dataset, as well as to identify the at-risk target groups.

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Relationship between pain and nonopioid substance use in two national samples of cancer survivors.

Pain and nonopioid substance use (tobacco, cannabis, alcohol) frequently co-occur, but have been understudied among cancer survivors. Even less work has examined whether pain and nonopioid substance use is related […]

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From Tics to Stabs: Renaming Cluster Tics in Cluster Headache-A Cross-Sectional Study.

Short-lasting paroxysms of facial pain in patients with cluster headache have traditionally been called “cluster tics.” Mostly described as co-occurring trigeminal neuralgia, they remain to be explored as an independent […]

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OnabotulinumtoxinA for primary new daily persistent headache and comparison to chronic migraine.

New daily persistent headache (NDPH) is an often treatment-refractory primary headache disorder with a lack of evidence base for treatment.

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Depression screening in migraine – A double-edged sword.

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Progress in multi-omics studies of osteoarthritis.

Osteoarthritis (OA), a ubiquitous degenerative joint disorder, is marked by pain and disability, profoundly impacting patients’ quality of life. As the population ages, the global prevalence of OA is escalating. […]

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Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain.

This multi-ancestry meta-analysis of genome-wide association studies (GWAS) investigated the genetic factors underlying chronic back pain (CBP) in a sample from the Million Veteran Program comprised of 553,601 Veterans of […]

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