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Role of magnesium-L-Threonate in alleviating skin/muscle incision and retraction induced mechanical allodynia and anxiodepressive-like behaviors in male rats.

Chronic postsurgical pain (CPSP) and its emotional comorbidities poses health burden to patients who have received the surgical treatment. However, its underlying mechanism remains unclear. Emerging studies indicate that magnesium […]

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Brain-Computer Interface to Deliver Individualized Multisensory Intervention for Neuropathic Pain.

To unravel the complexity of the neuropathic pain experience, researchers have tried to identify reliable pain signatures (biomarkers) using electroencephalography (EEG) and skin conductance (SC). Nevertheless, their use as a […]

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Effectiveness of non-immersive virtual reality in the management of procedure-related pain in preschool children: a randomized clinical trial.

The objective of this study is to assess the effectiveness of non-immersive virtual reality as a pain-distraction measure in children between the ages of 3 and 5 years undergoing painful injection […]

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Are postoperative opioid stewardship protocols sustainable? Results from a 2-year quality improvement project.

Opioid stewardship protocols reduce opioid overprescription, but many require corrective action within 1 year. Because there are limited data on the sustainability of opioid reduction protocols, we sought to evaluate […]

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Presenting a sham treatment as personalised increases the placebo effect in a randomised controlled trial.

Tailoring interventions to patient subgroups can improve intervention outcomes for various conditions. However, it is unclear how much of this improvement is due to the pharmacological personalisation versus the non-specific […]

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Addressing Bias in Acute Postoperative Pain Management.

This review evaluates disparities in acute postoperative pain management with regard to gender, race, socioeconomic status, age, and language. Strategies for addressing bias are also discussed.

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Virtual embodiment in fibromyalgia.

Chronic pain alters the experience of owning a body and leads to disturbances in bodily perception. We tested whether women with fibromyalgia (FM) are receptive to bodily illusions of owning […]

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Editorial: Psychological therapies for the management of chronic pain.

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Information theory and headache triggers.

This secondary analysis evaluated the information content exhibited by various measurement strategies of commonly perceived causes, or “triggers,” of headache attacks.

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Abuse and addiction in gabapentinoid drug users for neuropathic pain.

Gabapentinoids are gamma-aminobutyric acid analogue agents used in the treatment of neuropathic pain. They are increasingly being abused to achieve euphoric and dissociative effects. This study aimed to determine drug […]

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