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Papers of the Week
Presenting a sham treatment as personalised increases the placebo effect in a randomised controlled trial.
Authors
Sandra DA, Olson JA, Langer EJ, Roy MAbstract
Tailoring interventions to patient subgroups can improve intervention outcomes for various conditions. However, it is unclear how much of this improvement is due to the pharmacological personalisation versus the non-specific effects of the contextual factors involved in the tailoring process, such as the therapeutic interaction. Here, we tested whether presenting a (placebo) analgesia machine as personalised would improve its effectiveness.