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Lifetime history of an anxiety or depression disorder and adherence to medications used for the acute treatment of migraine.

In this secondary analysis of mobile health headache diary data, we evaluated the relationship between adherence to medication used for the acute treatment of migraine and lifetime history of an […]

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Small fiber neuropathy and intractable scalp pruritus in dermatomyositis patients.

Scalp pruritus is a common symptom in Dermatomyositis (DM) patients. There are indications that small nerve fibers neuropathy could be involved in this symptom, however the etiology of scalp pruritus […]

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Self-reported physical function is strongly related to pain behavior and pain interference and weakly related to physical capacity in people with chronic low back pain.

Inclusion of self-reported and capacity-based measures may help to further elucidate the interactive link between how people think and move.

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The role of pain catastrophizing in pain perception among patients with rheumatoid arthritis without clinical signs of inflammation.

Pain in rheumatoid arthritis (RA) is considered to be associated with non-inflammatory factors, including physical disabilities, psychiatric disorders, and pain catastrophizing (PC). PC is reportedly a key driver in the […]

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Depression and anxiety in women with idiopathic intracranial hypertension compared to migraine: A matched controlled cohort study.

To evaluate mental health burden in women with idiopathic intracranial hypertension (IIH) compared to matched women with migraine and population controls.

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Pain acceptance and psychological inflexibility predict pain interference outcomes for persons with chronic pain receiving pain psychology.

Awareness (being present), acceptance, and engagement (committed action) are three dimensions of psychological flexibility. Understanding these in the context of chronic pain may identify treatment targets to help refine individual […]

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Polygenic Contributions to Chronic Overlapping Pain Conditions in a Large Electronic Health Record Sample.

Chronic overlapping pain conditions (COPCs) are believed to share common etiological mechanisms involving central sensitization. Genetic and environmental factors putatively combine to influence susceptibility to central sensitization and COPCs. This […]

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The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens.

Stress suppresses the sense of pain, a physiological phenomenon known as stress-induced analgesia (SIA). Brain orexin peptides regulate many physiological functions, including wakefulness and nociception. The contribution of the orexinergic […]

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High fat/high sucrose diet worsens metabolic outcomes and widespread hypersensitivity following early life stress exposure in female mice.

Exposure to stress early in life has been associated with adult-onset co-morbidities such as chronic pain, metabolic dysregulation, obesity, and inactivity. We have established an early life stress model using […]

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Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews.

To provide a comprehensive overview of the efficacy, safety, and tolerability of antidepressants for pain according to condition.

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